Management and prognosis of pediatric status epilepticus

Abstract Background Pediatric status epilepticus is a neurological emergency with the potential for severe developmental and consequences. Prompt diagnosis management are necessary. Objectives To outline existing best available evidence managing pediatric neonatal epilepticus, in light of emerging randomized controlled studies. We also focus on short long-term prognoses. Materials methods This systematic overview literature. Results Status its treatment, prognosis usually based continuation seizure activity at 5 30 min. Refractory super-refractory further complicates requires continuous EEG monitoring regular reassessment adjustment therapy. Benzodiazepines have been accepted as first line treatment basis reasonable evidence. Emerging trials demonstrate equal efficacy parenterally administered phenytoin, levetiracetam, valproic acid second-line agents. Beyond this, third-line options sparse. However, encouraging midazolam ketamine exists data required immunological, dietary, surgical interventions. Conclusion Our emphasizes need evidence-based guidelines to manage that fails respond treatment.